Hubei natives are also taking the chance to return home from elsewhere in China.
Guo Wei, a teacher who works in Beijing, told AFP she had grabbed the first available ticket back to her hometown on Wednesday morning.
It was the first time she had been able to return to Hubei since the epidemic started, she said.
“It’s been too difficult!” she said, getting off the train with several bags.
People are now allowed to travel in or out of Hubei as long as they have a “green” health code issued by authorities showing they are not infected by the virus which has claimed more than 3,200 lives in China.
Beijing ordered the shutdown of Hubei in January to contain the spread beyond the province but has been gradually easing rules as numbers have dwindled.
In recent days residents have been allowed to move about and return to work — although schools remain closed.
At a highway checkpoint outside the Hubei city of Xiaogan, a teacher told Xinhua he was heading back to school in southern Guangdong province.
“I’ve stayed in Xiaogan for over two months,” he said, adding it would take him 14 hours to complete the journey.
“I’m very happy to be finally returning to work.”